Symptoms of esophageal cancer in advanced stage include difficulty in swallowing, pain and food reflux, etc. It is recommended to go to hospital for treatment in time. 1. Difficulty in swallowing: esophageal cancer is a malignant tumor originated from mucosal epithelium of esophagus. Patients with advanced stage of esophageal cancer show symptoms such as difficulty in swallowing and drinking. 2. Reflux: esophageal cancer in advanced stage can manifest food reflux symptoms, and the main symptom is esophageal obstruction. When patients’ tumor proliferation causes obstruction of esophagus, mucus accumulates in esophagus and causes reflux. When patients have reflux symptoms, it will also cause choking and coughing, or even aspiration pneumonia. 3. Pain: esophageal cancer in late stage manifests as pain, but the pain may involve the interscapular region of back, neck, back, forehead and other locations, and the pain of patients is persistent and severe. Therefore, when diagnosed with esophageal cancer, treatment should be carried out in time to avoid adverse effects and affecting health.