A small number of deeply stained heterotypic cells are often associated with tumors, but some of them are not necessarily tumor cells and need to be further examined to determine. Deeply stained heterogeneous cells are a kind of cell morphology between normal cells and cancer cells, with deeply stained nuclei. Heterogeneous cells are generated by many factors, such as apoptosis or gene mutation, and may be associated with bacterial or viral infections. The presence of a small number of deeply stained heterogeneous cells may be suspicious for tumor cells, but part of the heterogeneity is not necessarily tumor cells. This is not diagnostic and requires further tissue biopsy and immunohistochemistry to aid in diagnosis. If a small number of deeply stained heterogeneous cells are present, it is recommended to go to a regular hospital to complete the examination, clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.