How many times high neuron-specific enolase is not certain that it is cancer, but the higher the indicator, the more likely it is. Neuron-specific enolase, referred to as NSE, is a relatively common tumor marker in the clinic, which normally stays within the range of 0~12.5μg/l. Mild fluctuations are mostly considered to be caused by inflammation, benign tumors, and normal physiological phenomena, and if it exceeds the normal range by many times, it may be caused by cancer, and the higher the indicator, the higher the possibility of cancer. However, neuron-specific enolase can only be used as a preliminary screening, and can be completely confirmed, after the discovery of abnormalities, we need to further improve the CT, MRI, and pathological tissue biopsy and other tests, in order to clarify the specific causes of the disease, and actively take targeted treatment to avoid delaying the condition.