Infantile atrial septal defects, which are atrial septal defects in children, are among the common types of congenital heart disease. There is no way to promote self-healing. Whether or not atrial septal defects in infants can heal on their own is related to the size of the defect. It is also known as self-healing, which means that it will heal naturally. Infantile atrial septum, which is poorly developed during embryonic development, can cause atrial septal defects. It is mainly divided into primary foramen ovale, secondary foramen ovale, venous sinus and coronary venous sinus atrial septal defects. Secondary foramen ovale is the most common type of atrial septal defect. Atrial septal defects are detected in babies in the neonatal period when a color ultrasound of the heart is performed. If the defect is less than three millimeters, it is not recommended to be too nervous, and most infants will heal naturally in about three months. It is recommended that babies have a repeat heart ultrasound at three months. For atrial septal defects larger than four millimeters, they usually do not heal on their own. It is recommended to take the doctor’s advice into account and have regular follow-ups at the hospital. Combined with the baby’s own condition, interventional sealing or surgery is necessary. To summarize, atrial septal defects in infants, if relatively small, have the possibility of self-healing. If it is bigger, it is recommended to consult a doctor in time to avoid serious effects.