The course of treatment for kidney-induced lower limb edema is related to the severity of the disease and the treatment modality, and needs to be judged on a case-by-case basis. Lower limb edema induced by renal disease is a common complication, which usually needs to be treated with diuretics such as furosemide and torasemide, urinary protein control drugs such as captopril, glucocorticosteroids such as prednisone, and immunosuppressants such as cyclophosphamide, etc. In case of mild edema in patients with nephritis, such as only bilateral ankle edema, the treatment course needs to be determined on a case-by-case basis. In case of mild edema in patients with nephritis, such as only bilateral edema of the ankles. With rest or symptomatic treatment, the edema can be reduced after about 1 to 2 weeks. If the edema is more serious, and the lower extremity edema is accompanied by abdominal effusion, pleural effusion or pericardial effusion, it may take about 1 month for the edema to subside. If the patient’s condition is more serious, such as recurrent or progressive kidney disease, it may take about 2 months for the edema to subside. During the treatment period, it is necessary to pay attention to the control of salt intake, and the diet needs to be reasonable. In addition, the application of the above drugs have certain risks, should be used under the guidance of a doctor, we recommend that the patient to the hospital in time, and follow the doctor’s instructions to standardize the treatment.