The lack of effect of medication for itchy throat and cough may be related to not finding the real cause of itchy throat and cough and not treating the cause. Itchy throat, cough may be caused by chronic pharyngitis, bronchitis, gastroesophageal reflux disease and other diseases, according to the cause of the disease, to take treatment. 1. Chronic pharyngitis: this is a recurrent infection of chronic pharyngeal diseases, in addition to itching throat, cough, but also sore throat, foreign body sensation and other symptoms, the condition of the repetitive difficult to completely get rid of the root of the disease, you can use compound borax solution, compound chlorhexidine gargle solution gargle. Can also contain throat tablets to relieve symptoms. If the condition allows, you can take laser, low temperature plasma and other treatments. 2. Bronchitis: mainly due to pathogen infection or physical and chemical stimulation of the bronchial mucosa caused by inflammation, may have an itchy throat, cough and other symptoms. Cough suppressants such as dextromethorphan can be taken to improve the symptoms, and if there is a basis for bacterial infection, anti-infective treatment with drugs such as cefixime can be given. 3. Gastroesophageal Reflux Disease (GERD): gastric contents reflux into the esophagus, pharynx and airway, resulting in symptoms such as itchy throat, cough, heartburn and chest tightness. Commonly used proton pump inhibitors such as omeprazole, gastric power drugs such as mosapride and other treatment. Apart from this, there are other diseases that can lead to symptoms such as itchy throat and cough. If the symptoms are not relieved or aggravated, it is recommended that the patient consult a doctor in a timely manner, complete the examination and then use medication reasonably according to the cause of the disease, so as to avoid delaying the condition.