Swelling of calves should be alert to lower extremity vascular disease, right heart failure, nephritis, cirrhosis, malnutrition and other diseases. 1. Lower extremity vascular disease: such as varicose veins, lower extremity arterial occlusive disease, etc., due to such diseases will lead to lower extremity venous and arterial circulation obstruction, resulting in the symptoms of calf swelling. At the same time, it may be accompanied by symptoms such as subcutaneous hard nodules, reddening of the skin and elevated skin temperature. 2. Right heart failure: When the right heart fails, the venous blood in the lower limbs can not flow back smoothly, and then the venous pressure will rise and cause edema of the lower limbs, resulting in swelling of the lower legs. 3. Nephritis: Suffering from nephritis or nephrotic syndrome will cause sodium and water retention, which will lead to calf swelling, and may be accompanied by some other symptoms, such as urinary retention. 4. Cirrhosis: Cirrhosis of the liver can lead to portal hypertension and hypoalbuminemia, which can also cause swelling of the calves. 5. Malnutrition: Chronic malnutrition can also cause malnutritional edema, resulting in swelling of the calves, and the body may be accompanied by abnormal thinness. Other conditions may also lead to swelling of the calves, should go to the hospital in time for examination, after clarifying the cause of the disease, under the guidance of the doctor for appropriate treatment.