Cerebral infarction calf swelling may be due to lower limb paralysis resulting in neurogenic edema, lower limb venous thrombosis, cardiac insufficiency, etc. Furosemide, hydrochlorothiazide, warfarin, digoxin and other medications can be given symptomatic treatment. 1. Neurogenic edema: if the paralyzed side of the calf is mildly swollen, considering the existence of neurogenic edema, it is recommended to actively rehabilitate and exercise, and can be combined with a small dose of diuretic and dehydrating drugs, such as hydrochlorothiazide and other symptomatic treatment. 2. Lower extremity venous thrombosis: the limitation of activity of the paralyzed side of the calf can lead to lower extremity deep vein thrombosis, resulting in swelling, braking is required, and anticoagulant drugs such as warfarin and rivaroxaban are given to treat the condition, and surgery is required to put in a filter to prevent pulmonary embolism if necessary. 3. Cardiac insufficiency: Cerebral infarction patients with cardiac insufficiency may also have swelling of calves, and need to be given drugs to improve cardiac function, such as digoxin, furosemide and other drugs for symptomatic treatment. Cerebral infarction calf swelling, it is recommended to consult a doctor in a timely manner, after the cause of the disease is clear, targeted treatment, do not blindly self-medication.