Nifedipine regular tablets take effect in 15 minutes after oral intake, extended-release tablets take effect 1 hour after intake, and controlled-release tablets take effect in about 4 hours. Nifedipine belongs to calcium antagonist, clinically there are many kinds of dosage forms, including ordinary tablets, extended-release tablets and controlled-release tablets, due to the different dosage forms of the onset of action and maintenance of efficacy of the time there are obvious differences. Nifedipine tablets have the fastest onset of action, and the antihypertensive effect can be realized within 15 minutes after taking the medicine, but the duration of the drug effect is shorter. The onset of action of extended-release tablets is about 1 hour, and the onset of action of controlled-release tablets is slower, about 4 hours after taking the medicine, the duration of action of extended-release tablets and controlled-release tablets is relatively longer. Nifedipine belongs to the western prescription drugs, the adverse effects of the drug are dry stools, lower extremity edema, reactive rapid heartbeat, gingival hyperplasia, etc. Allergy to the components of the drug, severe aortic stenosis, patients taking rifampicin are prohibited. Clinical use of nifedipine to reduce blood pressure, follow the doctor’s instructions to choose the appropriate dosage form and dosage.