Pimples on both sides of the cheeks, also known as acne, is a chronic inflammatory skin disease of the sebaceous gland unit of the hair follicle, and can be removed by general treatment, medication, and physical therapy. 1. General treatment: keep the local skin clean, choose warm water or mild cleansing products, avoid exposure to the sun and staying up late, avoid high sugar, greasy and spicy food stimulation, and keep a relaxed mood. 2. Medication: Vitamin A acid, benzoyl peroxide, erythromycin ointment and fusidic acid cream can be used under doctor’s guidance, and oral isotretinoin and erythromycin can also be used, and methylprednisolone and other hormonal drugs can be used for treatment if necessary. 3. Physical therapy: including photodynamic therapy, which is mainly applicable to mild and moderate skin lesions, and laser therapy, which is mainly applicable to scar treatment. It is recommended to go to the hospital in time and standardize the treatment under the doctor’s guidance to avoid delaying the condition.