Methylprednisolone tablets have been shown to be effective in the treatment of some rheumatic diseases, endocrine disorders diseases, and edema. Side effects include metabolic and nutritional disorders, musculoskeletal and connective tissue abnormalities. 1. Efficacy: Methylprednisolone tablets are systemic corticosteroid drugs. It can only be used as symptomatic treatment, and can only be used as alternative medicine in certain endocrine disorders. Including rheumatic diseases, allergic diseases, tumors, edema, organ transplantation, endocrine disorders and other diseases. The glucocorticoids in methylprednisolone tablets diffuse through cell membranes and bind to specific receptors in the cytoplasm, which then synthesize various enzyme proteins. Through these enzymes play a variety of roles, glucocorticoids not only have an important effect on inflammation and immune processes, but also affect carbohydrate, protein and fat metabolism, and also have an effect on the cardiovascular system, bone marrow and muscular system and the central nervous system. 2. Side effects: Metabolic and nutritional disorders include fluid retention, sodium retention. Musculoskeletal and connective tissue abnormalities include growth retardation, muscle weakness. Peptic ulcer perforation and ulcer bleeding may also occur. Also, it is contraindicated in patients who are allergic to methylprednisolone tablets. Caution is required in children, diabetics, hypertensive patients and patients with a history of psychiatric disorders. Patients are advised to use this medication under the supervision of a doctor and should not use it privately.