A diagnosis of coronary artery disease can be confirmed if there is a definite 50% narrowing of the arteries of the heart, and the ability to control the disease for 30 years is related to whether or not aggressive treatment is administered. Patients with coronary artery disease can control the disease for 30 years if it is controlled by long-term medication, which can greatly reduce the probability of acute complications and have no significant impact on life expectancy. Patients need to take regular medications on time, including drugs to improve ischemia, such as propranolol and isosorbide nitrate; antiplatelet drugs, such as aspirin; and lipid-lowering drugs, such as atorvastatin. If a 50% coronary artery stenosis is found without appropriate treatment and the stenosis continues to worsen, even beyond 75%, stenting or bypass grafting is required. It can also lead to rupture of unstable plaque to form a thrombus and myocardial infarction, affecting the patient’s prognosis. If the diagnosis of 50% coronary artery stenosis, should be consulted in the Department of Cardiology under the guidance of a specialized physician for standardized treatment to slow down the progress of the disease, improve the prognosis, prevent complications, it is possible to control the condition within 30. Patients with 50% cardiac arterial stenosis should seek timely medical attention to avoid progression of the disease.