Chronic hepatitis B virus infection is a serious threat to human health, and it has been established that chronic hepatitis B virus infection can develop into chronic hepatitis, cirrhosis and liver cancer. How to prevent and treat? 1. Prevention Eighty percent of chronic hepatitis B virus infections in China are transmitted from mother to child, so blocking mother-to-child transmission is a top priority. Measure one, 6-7 months of pregnancy expectant mothers intramuscular injection of hepatitis B high efficiency immunoglobulin, once a month intramuscular injection, each time 200 units. Measure 2: Newborns are given 200 units of hepatitis B highly effective immune globulin and hepatitis B vaccine. 2. Treatment i. For patients with chronic hepatitis B virus infection, they should have regular checkups of liver function, hepatitis B virus quantification, liver fibrosis, and liver B-ultrasound. For patients with chronic hepatitis B, active antiviral treatment is required. Patients with cirrhosis should be treated with active antiviral and hepatoprotective therapy and regular rechecking of alpha-fetoprotein and liver B-ultrasound to detect early liver cancer in time. 4. For solitary liver cancer or small liver cancer, early surgery should be performed.