Cramps at night are associated with cold, muscle fatigue and calcium deficiency and can be disposed of through general treatment and medication. It is better to follow the doctor’s instructions and personalize the treatment. 1. Cold: Cramps can be triggered by a lack of bedding at night or a cold bedroom temperature. In this case, you should correct the bad living environment and keep warm, which can effectively improve the symptoms of cramps. 2. Muscle fatigue: Muscle fatigue caused by too much work or activity during the day can also trigger cramps. In this case, you should pay attention to rest and avoid exertion. Massage can also be taken to dispose of. 3. Calcium deficiency: For cramps caused by calcium deficiency, calcium gluconate and other medications can be applied under the guidance of a doctor for supplementation, and vitamin D can also be applied at the same time for treatment. Cramps caused by different reasons, the corresponding treatment measures, must follow the guidance of the doctor, to avoid blindly use their own medication.