Swelling of the lower limbs may be caused by pregnancy, and usually no medication is needed. If it is due to glomerulonephritis, heart failure and other diseases, you can take hydrochlorothiazide, furosemide and other diuretics as prescribed by the doctor, and if necessary, surgical treatment. 1. Pregnancy: After pregnancy, the increasing size of the fetus will compress the venous blood vessels of the lower extremities, resulting in obstruction of venous blood return to the lower extremities, thus causing swelling of the lower extremities. The edema of lower limbs caused by pregnancy usually does not need medication, and the edema symptoms will disappear gradually after the fetus is delivered and the compression of lower limbs is lifted. 2. Glomerulonephritis: This disease often leads to urine abnormalities such as hematuria and proteinuria, as well as edema of the lower limbs and elevated blood pressure. As the disease is self-limiting, patients can take hydrochlorothiazide, furosemide and other diuretics as prescribed by the doctor for treatment to improve the edema of the lower limbs. 3. Heart failure: The disease is mainly characterized by left heart failure in the early stage, and when right heart failure is induced with the development of the disease, it will lead to jugular venous aneurysm, abdominal distension, dyspnea, lower limb edema and other symptoms. Patients can take diuretics such as hydrochlorothiazide under the guidance of doctors to improve, at the same time, patients also need to seek medical treatment as soon as possible. Clinical causes of lower limb edema are many, it is recommended that the patient first consult a doctor for examination, to clarify the specific causes of the disease, and then follow the doctor’s instructions to use medication to avoid unauthorized medication.