Women who are positive for HPV 16 and 58 can have intercourse if it has not caused cervical lesions and is not being treated, although it is best to use a condom throughout. If it has caused cervical lesions, you should not have intercourse during and for a short time after treatment. Positive for HPV 16 and 58 indicates infection with high-risk human papillomavirus types 16 and 58, and requires cervical TCT and, if necessary, colposcopy for biopsy. 1. If there is no abnormality in the cervical TCT examination, this situation can be left untreated, but should be regularly rechecked, you can also have intercourse, but you should use a condom throughout the time of coitus. You should pay attention to exercise, increase immunity, and have regular checkups. 2. If there is an abnormality in the cervical TCT examination, it means that HPV types 16 and 58 infection has caused cervical lesions. If it is a low-grade lesion, you may need to use interferon suppositories and other drugs for treatment, and you can’t have coitus during the medication; if it is a high-grade lesion or cervical cancer, you need to have an operation, and you can’t have coitus for 1-3 months after the operation, depending on the operation.