Dense diffuse enhancement of echoes in the liver in the form of dots is an abnormal manifestation found in ultrasonography, which may be caused by fatty liver or other causes of diffuse liver injury, and it is recommended to go to the hospital for examination before treatment. Fatty liver is the excess of fat content in liver cells, which may be caused by long-term alcohol consumption, or may be caused by obesity and diabetes, often found during ultrasound examination, and may be manifested as diffuse echogenic enhancement. Viral hepatitis, pharmacological liver injury, autoimmune liver disease can cause hepatocyte edema, degeneration, will also appear in the liver echo diffuse enhancement. Patients are advised to further examine liver function, viral hepatitis indicators, autoantibodies, abdominal enhanced CT or nuclear magnetic, and ask about past medical history, alcohol consumption and drug history to determine the cause of liver injury, and perform liver puncture biopsy if necessary. When any abnormality occurs, it is important to consult a doctor in time to avoid delaying the condition.