Currently there is no clinical constipation treatment drug that can be taken for a long period of time without side effects. For difficult bowel movements caused by hard and dry stools, lubricating laxatives can be used, such as glycerin enemas, corkscrews, glycerin suppositories and so on. For constipation caused by diabetes and aging, osmotic laxatives such as lactulose and polyethylene glycol 4000 can be used. 1. For difficult bowel movement caused by hard and dry stools, lubricating laxatives can be used, which can soften the stools and lubricate the intestinal wall, so that the feces can be easily discharged. Adverse reactions have not been reported, but note that enemas are contraindicated in patients with bowel perforation, hemorrhoids with bleeding, and severe abdominal pain. 2. For constipation caused by diabetes mellitus and aging, osmotic laxatives can be used to form a hypertonic state in the intestines, absorb water, increase the volume of feces, stimulate intestinal peristalsis, and promote defecation. It is mild in action, effective for diabetic and elderly patients, and has mild side effects. It is suitable for patients with mild and moderate constipation. 3. Osmotic laxatives may cause abdominal distension after use. Note that lactulose is contraindicated in patients with galactosemia, intestinal obstruction and acute abdominal pain. Polyethylene glycol 4000 is contraindicated in patients with small bowel or colon disorders. magnesium sulfate is contraindicated in patients with phenobarbital poisoning. Patients should use the relevant drugs under the guidance of a specialized physician and strictly comply with medical advice.