Endometrial shedding is the phenomenon of shedding of the endometrium under the influence of different factors. Physiological endometrial shedding generally refers to female menstruation, which is a normal metabolic process of the body under the influence of estrogen or progesterone. There is a certain periodicity and self-limitation. In addition, some pathological reasons may also lead to abnormal endometrial shedding.1. Endocrine disorders: Commonly, excessive secretion of estrogen in the body may lead to irregular shedding of endometrium, which is manifested by normal endometrial shedding cycle but accompanied by abnormal bleeding symptoms. Progesterone, chorionic gonadotropin and other drugs can be used for treatment; 2, infection: endometritis caused by various pathogens is common, which may result in increased bleeding and prolonged endometrial shedding cycle, and may be accompanied by symptoms such as peritonitis and urinary tract infection. You can take antibiotics as prescribed by your doctor for treatment; 3. Polyps: endometrial polyps can also cause symptoms of abnormal endometrial shedding, manifesting as prolonged or shortened endometrial shedding cycles, and may be accompanied by abnormal bleeding between endometrial shedding periods. Some endometrial polyps will disappear spontaneously. In case of abnormal enlargement, the polyps can be surgically removed; 4. Hyperplasia: adult non-menopausal women with inter-epidymal bleeding, prolonged inter-epidymal bleeding or increased bleeding symptoms may be accompanied by irregular uterine bleeding symptoms, and in severe cases, the risk of complications of infertility or endometrial cancer. It can be treated by general treatment methods to exclude the cause, together with appropriate medications, and if necessary, it needs to be treated by surgical methods such as hysterectomy.