The whole body has no strength to feel tired may be caused by lack of sleep, colds, depression, etc. It is recommended that patients be treated according to different symptoms, pay attention to daily routine and avoid staying up late. 1. Lack of sleep: generally not much sleep or poor sleep quality, the body, the brain does not get enough rest and recuperation, easy to appear uncomfortable symptoms, such as feeling weak and tired. Patients should pay attention to daily rest and avoid exertion. 2. Cold and flu: not paying attention to warmth can cause wind-cold flu, which is characterized by nasal congestion, fatigue, muscle aches and pains and other symptoms. Patients can use medication, such as cold and flu granules, under the advice of the doctor. 3. Depression: It is generally manifested as lack of interest in doing things on a daily basis, lack of motivation, mental tension and physical exertion. Patients are introverted, sentimental and dependent. It is recommended that the patient timely treatment, psychotherapy and drug treatment under the diagnosis of the doctor. The whole body has no strength to feel physically tired to exclude physiological conditions, etc., long time not relieved or accompanied by other discomforts, should promptly consult a doctor.