Erythrocyte sedimentation rate of 28, if it is physiological is not serious, if it is pathologic, need to combine with the condition of comprehensive judgment. Erythrocyte sedimentation rate, also known as blood sedimentation, the normal value is <20mm/h, mild increase in blood sedimentation can be up to 25mm/h, moderate increase in blood sedimentation can be up to 50mm/h, and severe increase in blood sedimentation can be more than 50mm/h. The causes of increased blood sedimentation can be divided into three categories: physiological factors, technical factors, and pathologic factors. 1. Physiologic factors: most common in women's menstrual period, more than 3 months of pregnancy, the elderly over 60 years old. 2. Technical factors: large changes in temperature during the test, tilting of the sedimentation tubes or the sedimentation frame. 3. Pathological factors: such as pneumonia, meningitis and other inflammatory diseases; major surgery, myocardial infarction and other tissue damage and necrosis; lung cancer, liver cancer and other malignant tumors; subacute infective endocarditis, black fever and other hyperglobulinemia; anemia; hypercholesterolemia; lead poisoning, arsenic poisoning and other metal poisoning. Based on the blood sedimentation results alone can not be diagnosed with a certain disease, found that the erythrocyte sedimentation rate of 28 is recommended to go to the hospital, improve the examination to clarify the cause of the disease, to give targeted treatment or treatment.