The reason for pain aggravation after spraying Yunnan Baiyao may be the cause of excessive injury, but also may be the skin broken, drug allergy or the wrong method of use and so on. Yunnan Baiyao aerosol is mainly used for acute, closed soft tissue injuries, etc. It has the effect of reducing swelling and relieving pain (eliminating swelling and pain). As the liquid will dilate the local blood vessels, it can improve blood circulation, thus reducing swelling and pain caused by closed injuries. However, in the case of fractures, ligament tears, etc., leading to local inflammatory edema, as well as bruising. The use of this drug may be ineffective or even cause increased bruising, swelling and pain due to its vasodilating effect. If the skin is broken or allergic to the drug, the drug may cause strong irritation to the area of application, leading to worsening of the painful symptoms. In addition, incorrect application methods such as spraying too close or for too long may result in localized frostbite, which can cause the symptoms of pain to worsen. The appearance of such symptoms continue not to relieve, need to go to the hospital in time to consult the doctor, to clarify the cause of the disease for targeted treatment.