Red spots on the glans without pain or itching may be caused by diseases such as glansitis, genital herpes, condyloma acuminatum and so on. Patients can follow the doctor’s instructions according to the different causes of the appropriate treatment, such as medication, physical therapy and so on. 1. Glans: If the glans is induced by bacterial infection, patients can apply penicillin, ceftazidime, levofloxacin and other antibiotics as prescribed by the doctor. If the glans is triggered by Candida albicans infection, it can be treated with oral fluconazole, itraconazole and other antifungal drugs. 2. Genital herpes: patients can follow the doctor’s instructions to take oral vaxilovir tablets, ganciclovir tablets and other antiviral drugs to treat, and usually keep the private hygiene dry. If the affected area is complicated by bacterial infection, it can be treated with antibiotic drugs such as mupirocin ointment. 3. Condyloma acuminatum: patients can follow the doctor’s instructions to use topical imiquimod cream and other immunomodulators class of drugs treatment. It can also be treated by freezing, laser, electrocautery, aminoketoglutaric acid photodynamic therapy and other forms of physical therapy. There are various reasons that lead to painless red spots on the glans, requiring different treatments. It is recommended that patients go to the hospital for relevant examinations to clarify the cause of the disease and then follow the doctor’s instructions to carry out the corresponding treatment.