Large right liver thickness may be caused by infectious diseases, occupational diseases and heredity, fatty liver and other reasons. 1. Infectious diseases: when hepatitis virus infects the patient and causes the patient to suffer from chronic hepatitis, due to the chronic stimulation of inflammation and the impairment of liver function, the liver will be compensated for the enlargement and thickening. 2. Occupational disease: when suffering from hepatocellular carcinoma, hepatic cysts and other occupational diseases, due to the cysts and tumors occupying a certain space, it will lead to liver enlargement and thickening. 3. Heredity: a small number of patients have congenital thickening of the liver, which may not be treated if the patients have no discomfort and no abnormal liver function. 4. Fatty liver: when patients consume too much greasy food or are obese, some liver cells will undergo steatosis, which will lead to partial impairment of liver function in severe cases, and then the liver will increase in thickness. It is recommended that patients seek medical advice in time to find out the cause, and under the guidance of the doctor for treatment.