The main difference between the 2-valent HPV E. coli vaccine and the adsorbed vaccine is that the vaccine production process is different, and the vaccination program is slightly different, but in other aspects, the two have similar effects.
The 2-valent HPV E. coli vaccine belongs to the domestic 2-valent HPV vaccine, which is suitable for females aged 9-45 years old to be vaccinated, and can better prevent HPV16 and HPV18 viral infections. 2-valent HPV adsorbed vaccine belongs to the imported 2-valent HPV vaccine, which is also suitable for the above mentioned viral infections as well as the above mentioned groups to be vaccinated.
The 2-valent HPV E. coli vaccine is produced using E. coli as the carrier, and is produced in large quantities at a low price. Two doses are usually required for the entire course of vaccination for persons aged 9 to 14 years, and three doses are required for persons aged 15 to 45 years.
The 2-valent HPV adsorbed vaccine is produced using insect cells as the expression system, with a smaller yield and higher price, and requires three doses for those aged 9 to 45 years.