Urine protein 2+ generally suggests that there is protein in the urine, which may be related to physiological conditions such as strenuous exercise, eating a large amount of high-protein food, this condition generally does not affect life expectancy; pathologic conditions such as nephritis, kidney stones, etc., the survival time and the severity of the disease, if the disease is mild, it may not affect the life expectancy of the patient, and if the disease is serious, the patient may only survive for a few years. 1. Physiological conditions: some patients have strenuous exercise or eat a lot of high protein food before urine protein test, which may lead to urine protein 2+. Usually it can be relieved after rest or light diet. This does not mean that there is an organic disease in the body, so it usually does not affect life. 2. Pathological conditions (1) Nephritis: Nephritis is mostly caused by autoimmune system disorder, which can be clinically manifested as hematuria, proteinuria, edema, hypertension, elevated blood creatinine, etc. If the pathological type is mild, such as microscopic lesion nephropathy, it can be clinically cured and does not affect the patient’s life span; if the pathological type is more severe, it may develop into uremia and die within a few years. (2) Kidney stone: After the stone damages the mucous membrane of the kidney, it may also cause the protein in the blood to enter the urine and cause the above situation. After timely treatment with laser lithotripsy and other methods, the patient can survive for a longer time; however, if the stone has caused hydronephrosis and renal atrophy, which seriously affects the renal function and causes the blood creatinine to rise, the condition may progress to uremia and death may occur within a few years. Urine protein 2 + patients should go to the hospital in time to do further examination, to clarify the specific cause of the disease, and choose the appropriate method of treatment.