Entecavir does not usually affect the HIV window period test. Entecavir is an antiviral drug that inhibits the replication of the virus by acting on the reverse transcriptase enzyme, but it does not block the virus from entering human cells, so Entecavir does not affect the HIV window period test. AIDS is a sexually transmitted disease caused by human immunodeficiency virus infection. If you have high-risk sex or other high-risk blood contact, you should have a nucleic acid test or antibody test 4 to 8 weeks after the high-risk contact, and if the test is still negative after 8 weeks, you can basically rule out the possibility of HIV infection. Window period examination, it is possible that the body is infected with the virus for a short period of time, has not yet produced antibodies, and can not be completely excluded.