Tacrolimus capsules and injections are commonly used to prevent or treat graft rejection after liver and kidney transplantation, tacrolimus eye drops can be used to treat spring keratoconjunctivitis, and tacrolimus ointment can be used to treat atopic dermatitis.
Tacrolimus is an immunosuppressive macrolide, which can inhibit T-cell activation and helper T-lymphocyte-dependent B-cell proliferation, as well as inhibit lymphokine production, with immunosuppressive effects. The commonly used clinical dosage forms of this drug mainly include capsule, injection, eye drops and ointment.
Among them, capsules and injections are mainly used for the prevention or treatment of graft rejection after liver and kidney transplantation; eye drops are mainly used for spring keratoconjunctivitis; ointment is mainly used for the treatment of patients with moderate to severe atopic dermatitis.
Side effects such as palpitations (rapid heartbeat, often accompanied by panic), tremor, headache, diarrhea, nausea, and lung function impairment can occur in some patients after using tacrolimus capsules and injections; side effects such as burning sensation, itching, and allergic reaction of the skin can occur after using tacrolimus ointment; side effects such as eye discomfort, eye irritation, and foreign body sensation can occur after using tacrolimus eye drops.
Those who are allergic to any of the components of this product, those who are allergic to other macrolides are prohibited from using any preparation of this drug, tacrolimus is prohibited for pregnant women.
CAUTION: Patients using tacrolimus are at increased risk of bacterial, viral, fungal, and protozoal infections, including opportunistic infections.
Patients should use tacrolimus as prescribed by their doctor.