Lactulose Oral Solution is generally not suitable for patients with renal failure. Lactulose oral solution is used to treat chronic functional constipation. Due to lactulose is not absorbed, excessive dose caused by abdominal discomfort, flatulence, nausea, anorexia, vomiting and other adverse reactions. Contraindications: appendicitis, intestinal obstruction, unexplained abdominal pain, acute abdomen and concomitant use of other laxatives are contraindicated. It is contraindicated in patients with diabetes mellitus and galactosemia. Lactulose and its components are contraindicated in those who are allergic to lactulose and its components. Lactose and galactose intolerance is prohibited. Contraindicated in patients with uremia. Caution should be exercised during the first 3 months of pregnancy, and should be used under the supervision of a physician if the patient is more than 3 months pregnant, lactating, elderly or has other diseases. If constipation occurs in patients with renal failure, it is recommended to consult the hospital in time and take the medication under the doctor’s guidance to avoid the adverse consequences of self-medication.