There are many causes of stomach pain, such as abdominal cold, gastric ulcer, gastric cancer, etc. There is no such thing as the fastest way to relieve stomach pain, but according to the specific situation of the patient, you can choose to use hot compresses on the abdomen, medication, radiotherapy, surgery, painkillers and so on to relieve the symptoms of pain. 1. Abdominal cold: patients who suffer from gastrointestinal spasm due to cold, which causes stomach pain symptoms, can use hot water bag locally to relieve the spasm symptoms, so as to improve the symptoms of stomach pain. 2. Gastric ulcer: (1) acid suppressant: patients with stomach pain can follow the doctor’s instructions to use drugs to suppress acid to relieve symptoms, such as omeprazole, rabeprazole, ranitidine, famotidine and other drugs. (2) Painkillers: patients with stomach pain can also use painkillers, such as belladonna, scopolamine and so on. (3) Gastric mucous membrane protector: gastric mucous membrane protector, such as colloidal bismuth pectin, aluminum thiogluconate, Rebapatide, teprenone and other medicines can also be used according to the doctor’s prescription to alleviate the symptom of stomach pain. 3. Gastric cancer: (1) Surgery: patients who meet the indications of surgery are recommended to have surgery as early as possible, such as major gastrectomy. (2) Drug treatment: according to the specific conditions of patients, fluorouracil, mitomycin, cisplatin, etoposide, trastuzumab and so on can be chosen for chemotherapy. (3) Radiotherapy: patients who need radiotherapy can choose preoperative radiotherapy or postoperative radiotherapy according to patient’s specific situation. (4) Use of painkillers: Ibuprofen, tramadol, aminophenol dihydrocodeine, oxycodone extended-release tablets, etc. are given in steps. There are many other methods that can be used to relieve stomach pain, it is recommended that such patients go to regular hospitals, cooperate with doctors to complete the relevant examinations, clarify the cause and actively deal with it.