A nodular calcified focus is seen in the S2 segment of the liver is a nodular mass with calcium salt deposits in the upper left outer lobe of the liver. There are many causes of hepatic calcified foci, such as: hepatic hemangioma, intrahepatic bile duct stones, tumors and so on. 1. Hepatic hemangioma: Hepatic hemangioma is a benign tumor caused by localized dilatation of blood vessels in the liver or proliferation of vascular endothelial cells. The tiny blood vessels in hemangioma may atrophy when they are underdeveloped and eventually be fibrotic, forming calcified foci. 2. Intrahepatic bile duct stones: Intrahepatic bile duct stones may cause local bile blockage, bile stimulation of bile duct fibrosis, deposition of biliary components, and eventually formation of hepatic nodular calcification. 3. Tumor: malignant tumor cells invade normal cells, causing them to degenerate and necrotic, and fibrous tissue replaces normal cells to form calcified foci; when tumor cells are immature and without sufficient blood supply, they will also apoptosis, which will be manifested as nodular calcified foci. If calcified foci are found in the liver and if they are large in size, it is recommended that the patient should improve the tumor markers and CT examination, and puncture biopsy if necessary. In daily life, pay attention to the regularity of work and rest, and develop good living habits to improve the quality of life.