Neuralgia caused by osteoporosis should be treated with medication, general treatment and surgery under doctor’s guidance. 1. Medication: Oral non-steroidal anti-inflammatory drugs can be taken to relieve pain, common ones are celecoxib, diclofenac sodium, etc. Oral medication can also be taken to inhibit drugs destroying bone cells, such as bisphosphonates such as alenphosphoric acid and other drug therapy. Neurotrophic treatment can be carried out, including intravenous methylcobalamin injection, ganglioside sodium injection, these drugs can promote nerve recovery. 2. General treatment: Calcium supplements can be taken to maintain bone health, and vitamin D can be used to increase intestinal calcium absorption. Daily intake of protein and food with high calcium content, such as milk, eggs, etc., can be increased, and adequate sun exposure can be maintained. 3.2. Surgical treatment: Surgical treatment can also be performed to remove the proliferated bone fragments when the compression symptoms caused by osteoporosis are serious. Surgery can restore the normal physiological structure of the spine and relieve the local nerve compression, so that the nerves can be restored more quickly. Patients are advised to eat more food with high calcium and phosphorus content, and pay attention to not smoking and drinking as much as possible. Osteoporosis patients should use the medication under the guidance of the doctor in sufficient quantity and course. Regular checkups should be paid attention to, and weight-bearing exercise should be avoided.