Horizontal lines across the bridge of the nose can be improved through daily care, botulinum toxin injections and hyaluronic acid fillers. Nose bridge wrinkles are mostly due to skin laxity, lack of water and other local skin folds, so the following ways to lighten, as follows: 1. Daily care: first of all, we should do a good job of skin moisturizing, apply skin care products with local massage to promote local blood circulation, usually increase the intake of fresh vegetables and fruits, and keep a happy mood. 2. Botulinum toxin injection: mainly used for dynamic wrinkles on the back of the nose, i.e., the daily said “rabbit lines”, can be under the guidance of a professional doctor through local injection of Botulinum toxin, through the inhibition of the contraction of the muscles of expression to improve the back of the nose lines. 3. Hyaluronic acid filler: mainly used for static wrinkles on the back of the nose, in the local filler to eliminate wrinkles at the same time, can also play a role in moisturizing, hydration, generally after an injection can be maintained for about six months. It can be combined with botulinum toxin injection at the same time in order to strengthen the therapeutic effect. For patients with horizontal wrinkles on the bridge of the nose, it is recommended that they go to a regular hospital and choose the appropriate treatment under the guidance of the doctor in order to obtain the best treatment results.