Heart fossa pain when pressed may be caused by gastritis, pleurisy, costochondritis and so on. 1. Gastritis: The painful part of gastritis is mainly located in the heart socket of the upper abdomen, and pain usually occurs when pressed. The pain usually occurs within half an hour after a meal. 2. Pleurisy: Pain when pressing the heart with the hand may be caused by pleurisy. Due to infection, autoimmune and other causes of pleurisy may produce symptoms such as heart pain and chest tightness. 3. Costochondritis: the pain caused by pressing the heart fossa is mainly caused by costochondritis, the pain is aggravated when pressing, usually the pain can be improved by oneself and usually does not cause serious effects to the patient. It is recommended to consult a doctor in time for relevant examination, according to the specific situation, under the guidance of the doctor, to carry out symptomatic treatment.