There is no specific data on the chances of success of IVF at age 50 with three generations. For a 50 year old woman with diminished ovarian function, the probability of success is also reduced. Usually, the success rate of third generation IVF is higher than that of normal IVF. 50-year-old women with reduced ovarian function and reduced number of follicles will have a lower probability of embryo screening, and the number of sacs that can be raised will be reduced, and the probability of fetal abnormality will be increased, and it may also affect the chance of embryo implantation, which will ultimately affect the success rate of IVF. Therefore, the success rate of three-generation IVF at the age of 50 will be lower compared to the normal level, and it is recommended that people who intend to do IVF at this stage should be psychologically prepared, and under the guidance of the doctor, they should conduct a detailed examination of the body data to determine whether it is suitable for cultivation or not. It is recommended that couples during the preparation for pregnancy go to the hospital for pre-pregnancy eugenic health checkups to assess whether the body is suitable for pregnancy; quit smoking and drinking, develop good living habits, and don’t stay up late. Moderate exercise to maintain good health, to avoid prolonged exposure to radiation or pollution in the environment, to get out of the toxic and harmful work environment; to maintain a happy mood; avoid heavy physical labor.