Multiple polypoid lesions of the gallbladder are polypoid lesions in which the wall of the gallbladder protrudes or bulges into the lumen of the gallbladder, and are most often detected on imaging studies. Polypoid lesions of the gallbladder are polyps formed when the wall of the gallbladder protrudes into the gallbladder cavity due to abnormal lipid metabolism in the bile and chronic inflammatory stimulation of the gallbladder. The majority of the population has no obvious symptoms, and most of them are detected during physical examination with abdominal ultrasound and other imaging tests. Some may present with symptoms such as right upper abdominal discomfort, loss of appetite, nausea, and vomiting. If the polyp is small and asymptomatic, no special treatment is needed, and the patient should follow the doctor’s instructions for regular checkups. However, if the polyp is large and the symptoms are obvious, it can be treated by surgery, and the specific treatment should be reasonable under the guidance of the doctor.