The treatment of a bulge by the knee needs to be targeted according to the cause of the bulge. If it is prepatellar bursitis, it can be removed by puncture or surgery; if it is joint effusion, it can be treated by joint puncture and intra-articular injection therapy. If the bulge is located in the lower part of the front of the knee, it may be prepatellar bursitis, which is usually caused by trauma or excessive friction. The bursa can be removed by puncture to extract the bursa fluid and then injected with dexamethasone or anhydrous alcohol to promote adhesion of the bursa wall, or surgically removed. If the bulge is located on either side of the patella, it may be caused by excessive fluid buildup in the knee joint. This can be treated with arthrocentesis to drain the fluid out of the joint and then inject sodium vitrate. After the puncture, a compression bandage is needed to prevent the fluid from seeping out again. If it is caused by osteoarthritis, anti-inflammatory and analgesic drugs can be taken orally, such as Nimesulide and Erythroxib. Glucosamine sulfate can also be taken orally for treatment. If it is caused by a tumor in the knee joint area, it can be treated by surgical resection or even amputation, along with radiotherapy. A bulge next to the knee that cannot be relieved on its own should be treated promptly.