The cost of liver replacement ranges from $200,000 to $800,000, depending on the patient’s condition, the hospital chosen, and local health insurance policies. The exact cost of liver replacement varies greatly, depending on the level of the hospital. Liver replacement is a complicated process. Liver replacement requires finding a matching liver, conditioning the patient’s body, etc., and the whole process will cost about 200,000 to 500,000 dollars. If the liver is donated by a relative, there is no need to pay for the liver source, and the cost will be around $200,000; if the liver source comes from a brain-dead patient, it will cost around $500,000 plus the cost of the liver source. If the patient’s liver is infected or rejected, or if he/she is suffering from other diseases, he/she will need to undergo anti-infection treatment and anti-immune rejection after the liver exchange, and the cost will be relatively higher, which may range from 500,000 to 800,000 yuan. If patients want to know the specific cost of liver replacement, it is recommended to consult with local regular hospitals.