Vitiligo phototherapy can be cured in some people. Vitiligo is a skin and mucous membrane pigmentation loss disease caused by melanin deficiency. The cause of vitiligo patients is unknown, but considered with autoimmune factors, oxidative stress, melanocyte self-destruction, genetic factors and many other factors related to the manifestation of white patches of skin and mucous membranes, which can be round, oval, linear or irregular shape, varying in size and other symptoms. Through the clinical formal treatment, can control the development of the disease, promote melanocyte regeneration, early active, standardized treatment can be significantly better, or even cure. Phototherapy methods to treat vitiligo, mainly through the use of narrow spectrum medium wave ultraviolet light (NB-UVB) and 308nm excimer laser, if necessary, combined with fractional laser, can treat various types of vitiligo, improve the symptoms, control the condition, can generally play a better effect, and part of the patient can achieve the effect of cure. It is recommended that patients diagnosed with vitiligo, timely to the regular hospital dermatology consultation, timely treatment in accordance with the doctor’s instructions, control the condition, improve the symptoms.