Chronic inflammation of the mucous membrane of the lesser curvature of the gastric sinus can be treated by adjusting the diet, taking medication and undergoing surgery. 1. Adjust the diet structure: keep regular diet, avoid spicy and stimulating food, don’t drink alcohol, don’t eat pickled products, can eat more protein, vitamin-rich, easy-to-digest food, to avoid the burden on the stomach and intestines. 2. Taking drugs: If the patient has more gastric acid secretion, you need to use drugs to inhibit gastric acid secretion, such as omeprazole enteric-coated capsules, cimetidine, etc. If there is damage to the gastric mucosa, you need to use drugs to inhibit gastric acid secretion. If accompanied by gastric mucous membrane damage, you can use gastric mucous membrane protective agents, such as magnesium aluminum carbonate, aluminum sulfate. If the phenomenon of insufficient gastric power, you can use gastric power drugs, such as Itopride, Domperidone, etc., and the above drugs should be taken under the guidance of a professional doctor. 3. Surgery: If the condition is serious and the first two ways cannot achieve the expected therapeutic effect, it can be treated by submucosal dissection under gastroscope. Patients with chronic inflammation of the mucous membrane of the lesser curvature of the gastric sinus should go to the hospital in time to receive examination and actively cooperate with the treatment, in order to prevent the aggravation of the condition affecting the life.