Delange syndrome is a rare condition of congenital dysplasia. Children suffering from this disease may develop severe mental retardation and are advised to seek prompt medical attention and standardized treatment after a thorough evaluation of the condition under the guidance of a doctor. The disease can lead to the failure of several organs in the body and therefore requires prompt treatment in a regular hospital. Dran Fever Syndrome is mainly manifested in special facial and upper limb reset defects, hirsutism, intrauterine growth of the fetus and postnatal development are delayed to varying degrees. Common organ abnormalities include ptosis, myopia, pyloric stenosis, congenital ventricular septal defects, epilepsy, and hearing loss. The condition can cause severe symptoms, and if the diagnosis has been made, it is important to promptly evaluate for organ abnormalities and correct the abnormal organs with symptomatic treatment first.