Generally speaking, biological patches do not need to be removed because they are non-degradable and ultimately bonded to the body, so they do not need to be removed if there is no rejection, infection, or recurrence. The raw material of bio-patch is derived from animal or human tissue or organ, not synthetic, and is made by further processing to remove rejection, so it is called bio-patch. While the bio-patch is degraded in the body, the body’s own connective tissue, normal cells, fibers, and blood vessels will enter the interior of the bio-patch, eventually replacing the original patch, and at the same time forming the body’s own new barrier, which theoretically coexists with the body and does not produce a reaction of rejection. In theory, it will coexist with the body and no rejection will occur. Therefore, normally, the biopatch does not need to be removed.