Subcutaneous fibrous tissue hyperplasia with hyperpigmentation, the treatment includes topical medication, laser treatment, surgery, general life treatment and so on. 1. Topical medication: Subcutaneous fibrous tissue hyperplasia with hyperpigmentation can be treated with medication such as retinoic acid cream and vitamin E cream to inhibit the formation of melanin, so as to achieve the purpose of lightening the pigmentation. 2. Laser treatment: When medication is not effective, laser therapy can be given to remove melanin particles. 3. Surgery: If the proliferation of subcutaneous fibrous tissue is large, the proliferated tissue can be surgically removed. 4. General life treatment: patients should do a good job of sunscreen to prevent melanin production, and at the same time pay attention to skin hygiene, inhibit the growth of bacteria and other microorganisms. The appearance of subcutaneous fibrous tissue hyperplasia with hyperpigmentation phenomenon, please consult a doctor in time, the above drugs must follow the doctor’s instructions.