The difference between immunoglobulin and albumin is mainly reflected in the different production sites and different effects. 1. Production site: immunoglobulin is mainly produced by plasma cells, while albumin is synthesized by liver cells. When the body is invaded by foreign pathogenic microorganisms, the immune system will produce antibodies against the foreign antigens, i.e. immunoglobulins. 2. Role: Immunoglobulin is a kind of antibody, with a protective effect, usually used in the treatment of secondary immunoglobulin deficiency disease and primary immunoglobulin deficiency disease to supplement the human immunoglobulin, play a role in strengthening immunity. Globulins can be categorized into different types such as IgG, IgE, and IgM. Elevated globulin can also be seen in autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. Albumin, on the other hand, is usually used to correct blood volume deficiencies and maintain plasma colloid osmolality. Abnormal values of globulin and albumin are recommended for prompt medical attention and symptomatic treatment.