The treatment of neuralgia does not exist absolutely fast, need to be under the guidance of neurological specialists normative use of drug therapy, including calcium ion regulators, sodium channel blockers, antidepressants, opioid analgesics and so on. 1. Calcium ion regulator: it is the drug of choice for neuralgia, including gabapentin and pregabalin. Adverse reactions include dizziness and drowsiness, ataxia, fatigue, etc. They are prohibited in acute pancreatitis and severe renal insufficiency. 2. Sodium channel blockers: such as oxcarbazepine, carbamazepine. Adverse reactions include dizziness, drowsiness, fatigue, elevated liver enzymes, skin rash, etc. They are contraindicated in patients with severe liver function abnormality and allergy to the drug. 3. Antidepressants: amitriptyline, venlafaxine and so on. Amitriptyline adverse reactions include dry mouth, constipation, sedation, dysuria, etc. It is prohibited in patients with severe heart disease and glaucoma. Venlafaxine adverse reactions include gastrointestinal reactions, tremor, fatigue, drowsiness, prohibited with monoamine oxidase inhibitors. 4. Opioid analgesics: such as morphine, oxycodone, etc., adverse reactions for gastrointestinal reactions, sedation, respiratory depression, prohibited in patients with respiratory insufficiency, severe hepatic and renal insufficiency. Some patients can also choose physical therapy such as ice, infrared irradiation, etc.; surgical treatment such as nerve block surgery, microvascular decompression surgery. Patients with neuralgia need to actively seek medical attention, clarify the cause under the guidance of the doctor, and strictly follow the doctor’s instructions to use medication or choose the appropriate treatment.