Quadruple therapy to take clarithromycin extended-release capsules the next morning pooped out for many reasons, such as indigestion, the capsule shell is not easy to digest, etc., can be improved by oral lactobacillus or change the medication to clarithromycin tablets and other methods. 1. indigestion: taking clarithromycin extended-release capsules the next morning will clarithromycin extended-release capsules intact discharge may be due to indigestion. The capsule shell in the gastrointestinal tract has not yet been digested, it is discharged from the body, can not play a medicinal effect, you can adjust the gastrointestinal function through dietary regulation, oral lactobacillus and other intestinal beneficial bacteria, digestive enzyme tablets, to promote digestion. 2. Adjustment of drugs: Clarithromycin extended-release capsules and clarithromycin extended-release tablets comparison, only the dosage form is different, the efficacy of the same. Clarithromycin extended-release tablets are more slowly absorbed, but no capsule shell, relatively easy to digest and absorb, so the extended-release capsules can be replaced by extended-release tablets to reduce the pressure of digestion, which is conducive to the absorption of the body. If the indigestion is serious, it is recommended to go to the hospital, under the guidance of the doctor, for targeted treatment.