Enlarged axillary lymph nodes may cause arm pain. Axillary lymph nodes are lymph nodes located in the armpits and are clinically called axillary lymph nodes. The axillary lymph node cluster collects lymphatic fluid from the upper trunk, breast, and chest wall, etc. There are various reasons for their enlargement, including inflammation, tumors, metastatic cancer, and immune disorders. Enlarged lymph nodes in the armpit can press on the surrounding tissues, resulting in soreness in the arm or radiating pain when the arm is moved and pulled. If the lymph nodes in the armpit are enlarged, the lymph nodes should be palpable. If the lymph nodes are not palpable, the arm pain may not be related to the lymph nodes in the armpit, but due to exertion. If you have enlarged axillary lymph nodes, go to the hospital immediately for examination and treatment after clarifying the cause of the disease. Do not delay as this may lead to serious consequences or even life-threatening situations.