Patients with hunger gastropathy usually exhibit symptoms such as abdominal pain, bloating, acid reflux, burping, heartburn, and loss of appetite. Starvation gastropathy generally refers to the feeling of stomach discomfort that occurs under the state of hunger, but there is no such thing as starvation gastropathy in the clinic. Clinically, the disease of stomach discomfort in the state of hunger is commonly seen as duodenal ulcer, a disease in which the duodenal mucosa is digested by gastric acid and develops ulcerative lesions due to excessive secretion of gastric acid or weakening of the duodenal mucosal defense function. Patients with starvation gastropathy often present with abdominal pain, bloating, acid reflux, burping, heartburn, and loss of appetite, and the abdominal pain is cyclical and rhythmic. Patients with abdominal pain episodes have a certain seasonality, mostly in the fall and winter or winter and spring alternation. The abdominal pain of duodenal ulcer is mostly related to eating, the pain is obvious when fasting (hunger), and can be gradually relieved after eating, and the pain is mostly attacked at night, which is manifested as nocturnal pain. If the patient has long-term or recurrent symptoms of stomach discomfort during hunger, it is recommended to seek timely medical treatment, improve gastroscopy, 13C breath test and other related examinations to identify the cause of the disease and carry out targeted treatment to avoid delaying the condition.