The normal Down screening, biochemical Down screening, is a fasting blood test, and the fee may not be the same according to the level of the hospital, about 200 yuan. Now there is another kind of Down screening is non-invasive DNA, also known as Down screening, in fact, non-invasive way will be more expensive, the price varies from region to region and from hospital to hospital, it may cost 1000-3500 yuan, it is a self-pay item.