What medication is good for dry mouth at night until 12 o’clock is mainly related to the cause of dry mouth. If it is caused by dehydration, there is no need to take medication, i.e. there is no such thing as a good medication. However, if it is caused by dry syndrome, then you can take drugs such as Hirsutine. Some people sleep at night to 12 o’clock appeared dry mouth, may be during the day to drink too little water caused. So at this time only need to be properly hydrated, no need to take drugs. However, if it is caused by dry syndrome, you can take Hirsutine to promote the secretion of salivary glands and relieve dry mouth. In addition, you can also apply some artificial saliva to relieve dry mouth. Symptomatic treatment should be accompanied by active standardized treatment of the primary disease. The application of drugs, need to be under the guidance of the doctor, do not apply on their own, or arbitrarily increase or decrease the dose.